Now showing items 1-6 of 6
A time-dependent role of midline thalamic nuclei in the retrieval of fear memory
Increasing evidence indicates that the medial prefrontal cortex (mPFC) and the amygdala mediate expression and extinction of conditioned fear, but few studies have examined the inputs to these structures. The dorsal part ...
The brain-derived neurotrophic factor Val66Met polymorphism predicts response to exposure therapy in posttraumatic stress disorder
BACKGROUND: The most effective treatment for posttraumatic stress disorder (PTSD) is exposure therapy, which aims to facilitate extinction of conditioned fear. Recent evidence suggests that brain-derived neurotrophic ...
Revisiting the role of infralimbic cortex in fear extinction with optogenetics
(Society for Neuroscience., 2015)
Previous rodent studies have implicated the infralimbic (IL) subregion of the medial prefrontal cortex in extinction of auditory fear conditioning. However, these studies used pharmacological inactivation or electrical ...
Systemic propranolol acts centrally to reduce conditioned fear in rats without impairing extinction
Background—Previous work has implicated noradrenergic beta-receptors in the consolidation andreconsolidation of conditioned fear. Less is known, however, about their role in fear expression and extinction. The beta-receptor ...
Erasing fear memories with extinction training
Decades of behavioral studies have confirmed that extinction does not erase classically conditioned fear memories. For this reason, research efforts have focused on the mechanisms underlying the development of extinction-induced ...
Correlations between psychological tests and physiological responses during fear conditioning and renewal
(BioMed Central, 2012)
BACKGROUND: Anxiety disorders are characterized by specific emotions, thoughts and physiological responses. Little is known, however, about the relationship between psychological/personality indices of anxiety responses ...